Genetic Recombination andCryptosporidium hominisVirulent Subtype IbA10G2

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Genetic Recombination and Cryptosporidium hominis Virulent Subtype IbA10G2

Little is known about the emergence and spread of virulent subtypes of Cryptosporidium hominis, the predominant species responsible for human cryptosporidiosis. We conducted sequence analyses of 32 genetic loci of 53 C. hominis specimens isolated from a longitudinally followed cohort of children living in a small community. We identified by linkage disequilibrium and recombination analyses only...

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Predominant Virulent IbA10G2 Subtype of Cryptosporidium hominis in Human Isolates in Barcelona: A Five-Year Study

BACKGROUND Cryptosporidium infection is a worldwide cause of diarrheal disease. To gain insight into the epidemiology of the infection in a certain geographic area, molecular methods are needed to determine the species/genotypes and subtypes. METHODOLOGY/PRINCIPAL FINDINGS From 2004 to 2009, 161 cryptosporidiosis cases were detected in two hospitals in Barcelona. Diagnosis was performed by mi...

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Biochemical mutants were obtained from Micromonospora chalcea, M. purpurea, and M. echinospora by using ultraviolet radiation or nitrosoguanidine. Crosses carried out between complementary nutritional mutants of the same species showed positive genetic interaction. Data are reported which indicate that the interaction between the crossed strains is due to genetic recombination. No evidence for ...

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Genetic recombination in plants.

Meiotic recombination generates novel allelic arrays on chromosomes. Recent experiments have revealed an extraordinarily nonrandom distribution of recombination breakpoints along the lengths of plant chromosomes; for example, recombination breakpoints often resolve within genic sequences, and thereby generate novel alleles. The mechanism by which recombination breakpoints are determined is an a...

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The application of genetic algorithms to optimisation problems for which the solution is a set or multiset (bag) is considered. A previous extension of schema analysis, known as forma analysis, is further developed and used to construct principled representations and operators for problems in this class. The extensions to forma analysis include the introduction of genes whose values cannot be a...

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ژورنال

عنوان ژورنال: Emerging Infectious Diseases

سال: 2013

ISSN: 1080-6040,1080-6059

DOI: 10.3201/eid1910.121361